99%HPLC N-Acetylneuraminic acid CAS 131-48-6

Neu5Ac acts as a receptor for influenza viruses, allowing attachment to mucous cells via hemagglutinin

Description:

N-Acetylneuraminic acid (Neu5Ac or NANA) is the predominant sialic acid found in mammalian cells.

This negatively charged residue is found in complex glycans on mucins and glycoproteins found at the cell membrane. Neu5Ac residues are also found in glycolipids, such as gangliosides, a crucial component of neuronal membranes found in the brain.

Along with involvement in preventing infections (mucus associated with mucous membranes — mouth, nose, GI, respiratory tract), Neu5Ac acts as a receptor for influenza viruses, allowing attachment to mucous cells via hemagglutinin (an early step in acquiring influenzavirus infection).

Application: 

Naturally widespread carbohydrate with numerous biological functions, including blood protein half-life regulation, variety of toxin neutralization, cellular adhesion and glycoprotein lytic protection. Starting reagent of biochemical derivatives for the synthesis pharmaceuticals.

 

 

1. Anti-virus function

2. Anti-cancer function

3. Anti-inflammation function

4. Defensive function against bacteriological infection

5. Controlling ability of immune system

6. in nerve cells

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99%HPLC N-Acetylneuraminic acid CAS 131-48-6